This book contains refereed papers which were presented at the 34th Workshop of the International School of Mathematics "G. Stampacchia,” the International Workshop on Optimization and Control with Applications. The book contains 28 papers that are grouped according to four broad topics: duality and optimality conditions, optimization algorithms, optimal control, and variational inequality and equilibrium problems. The specific topics covered in the individual chapters include optimal control, unconstrained and constrained optimization, complementarity and variational inequalities, equilibrium problems, semi-definite programs, semi-infinite programs, matrix functions and equations, nonsmooth optimization, generalized convexity and generalized monotinicity, and their applications. Audience This book is suitable for researchers, practitioners, and postgraduate students in optimization, operations research, and optimal control.