Workers in analytical chemistry are provided with a starting place for information about instrumental techniques, including both a basic introduction and the important references on the theory and methodology for each technique. All of the chapters that appeared in the second edition have been thoroughly expanded and updated with new concepts, applications, and key references to the recent literature. In addition eight new chapters have been added, covering topics such as: * microchip and biosensor technologies * validation of chromatographic methods * gel permeation * field-flow fractionation, * countercurrent chromatography * thin-layer chromatography. This insightful and thorough text would be a valuable edition to the collection of any analytical chemist, chemical engineer, lab technician or researcher.