This book contains the carefully selected best papers of the 8th International Conference on Enterprise Information Sysetms, ICEIS 2006, held in Paphos, Cyprus, in May 2006. The 4 invited papers and 27 revised and selected papers presented in this volume cover different aspects related to enterprise computing. They were selected from 63 accepted papers (out of more than 400 submissions). The contributions are grouped in sections on databases and information systems integration; artificial intelligence and decision support systems; information systems analysis and specification; software agents and internet computing; and human-computer interaction.