-- Impact of antagonist peptides on understanding T-cell signaling and thymic selection-- Role of DM in antigen presentation by class II MHC-- Role of JAK and STAT in signal transduction by cytokine receptors-- Dynamics of HIV infections-- Conditional mutant mice in the study of immunity-- Sections on Ig genes refocused to reflect the complete sequencing of human V genes-- Sections on regulation of immune responses revised to reflect new understanding of the role of TH1 and TH2 cells-- Lectin pathway in innate immunity-- Completely revised section on AIDS-- Completely revised section on tumor immunity-- Late phase events in allergic reactions-- Latest advances in B and T cell signaling pathways and antigen processing pathways