This classic text gives a uniquely lucid and lively view of neurotransmitters, their role in nervous system function, and their involvement in the mechanisms of psychiatric drug action. For three decades it has served as an essential guide for students of neuroscience and psychopharmacology,residents in psychiatry and neurology, and clinicians and scientists. Both authoritative and very readable, it has been thoroughly updated for each edition. In the Eighth Edition more space is devoted to clinical examples, subclasses of receptors that provide targets for new drugs, moleculargenetics, the major problem of drug delivery to the brain, and the growing recognition of nicotinic receptors in the brain and their possible involvement in Alzheimer's and Parkinson's diseases. In addition, the book's format has been enlarged and a second color added to many of theillustrations.