As progress in science continues to reveal unimagined complexities, three scientists revisit the difficult and compelling question of the origin of our universe. As mathematician, biochemist, and philosopher of science, they explore the possibility of developing a reliable method for detecting an intelligent cause and evidence for design at the origin of life. In the process, they present a strong case for opening and pursuing a fruitful exchange between science and theology. Mathematician William Dembski, author of The Design Inference, first argues that new developments in the information sciences make intelligent design objectively and scientifically detectable--he identifies the signs of design. Next, philosopher of science, Stephen Meyer, and biochemist Michael Behe, author of Darwin's Black Box, argue that these signs are now clearly evident in both the architecture of the universe and the features of living systems. Other essays by the authors defend the scientific status of the theory of intelligent design and show how that theory supports traditional religious belief without necessarily "proving" the existence of God. In a concluding essay, Michael Behe responds to critics of his best selling book, Darwin's Black Box, thus bringing readers up-to-date on the status of the contemporary design argument in biology.