In the earliest battles against the monstrous Angels, young Eva pilots Shinji and Rei were forced to carry humanity's hopes on their shoulders. Now, with the deadly onslaught of the Angels escalating and the apocalyptic Third Impact looming, Shinji and Rei find their burden shared by two new Eva pilots, the fiery Asuka and the mysterious Mari. Maneuvering their enormous Eva machines into combat, the four young souls fight desperately to save mankind from the heavens.