Three gangs. Five girls. No way out. Machete Betty leads a small gang of women under the self-appointed task of protecting their home of Old Beach, one of three boroughs surrounding a rich metropolitan city. When Betty takes the life of a rival gang member in an act of self-defense, she sets off a chain reaction of retaliation, gang warfare, and unlikely allies. It's up to the The Fever-Machete Betty, Derby Girl, Bloody Mary, Daisy Chain, and Violet Volt-to defend their turf at all costs.