Early in the 21 Century, the Tyrell Corporation advanced robot evolution to the Nexus phase - creating artificial beings virtually identical to humans - known as replicates. After Replicates were declared illegal on Earth, special police operatives - called Blade Runners - had orders to kill or 'retire' any trespassers on detection. Aahna 'Ash' Ashina of the Los Angeles Police Department is assigned to investigate the disappearance of Isobel and Cleo Selwyn, the wife and daughter of business tycoon Alexander Selwyn. Ash finds the debris of Isobel's spinner in a downtown slum, along with the body of Selwyn's chauffeur. Before she can investigate further, Ash's cybernetic back brace shuts down and she collapses. Meanwhile, Isobel and Cleo, alive and alone, make their way through the rain soaked city, searching for a contact that will lead them to safety, far from Alexander Selwyn…