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Happy Accidents: Serendipity in Modern Medical Breakthroughs

por Morton A Meyers MD

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1245220,184 (3.5)2
Happy Accidents is a fascinating, entertaining, and highly accessible look at the surprising role serendipity has played in some of the most important medical discoveries in the twentieth century. What do penicillin, chemotherapy drugs, X-rays, Valium, the Pap smear, and Viagra have in common? They were each discovered accidentally, stumbled upon in the search for something else. In the 1990s, Pfizer had high hopes for a new drug that would boost blood flow to the heart. As they conducted trials on angina sufferers, researchers noted a startling effect: while the drug did not affect blood flow to the heart, it did affect blood flow elsewhere! Now over six million American men have taken Viagra in their lifetime. Winston Churchill once said, "Men occasionally stumble across the truth, but most of them pick themselves up and hurry off as if nothing has happened." Within the scientific community, a certain stigma is attached to chance discovery because it is wrongly seen as pure luck. Happy accidents certainly happen every day, but it takes intelligence, insight, and creativity to recognize a "Eureka, I found what I wasn't looking for!" moment and know what to do next. In discussing medical breakthroughs, Dr. Morton Meyers makes a cogent, highly engaging argument for a more creative, rather than purely linear, approach to science. And it may just save our lives!… (más)
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Mostrando 5 de 5
A series of entertaining reconstructions of key scientific discoveries that were largely happenstance. The book is informative, fun and leaves you with a view of science that is much less mysterious and a lot more luck and politics.

The book emphasises the medical sciences which are a bit particular in comparison fo others in their ethical aspects and complexity. ( )
  yates9 | Feb 28, 2024 |
3/24/22
  laplantelibrary | Mar 24, 2022 |
Meyers's contention is that scientific discoveries of the paradigm-shifting sort are not generally made by rote testing of compounds (for example), but by serendipitous accidents that are recognized as significant. His examples generally, though not always, support this position. It's clear from the degree to which he becomes exercised that cancer research was the impetous for this book. ( )
  OshoOsho | Mar 30, 2013 |
Fast -reading very interesting history of scientific discovery that occurs while looking for something else. A dust mote of common mold makes its way to an unwashed petri dish and leads to penicillin. A common rye fungus and fortuitous weather conditions leads to the Salem witch trials and acid trips on LSD. A side-effect of a tuberculosis drug leads to a pill for delirious schizophrenics. The book is an ode to the nerdy loner scientists we all laughed at in middle school. Long may they prosper and discover! ( )
1 vota kageeh | Oct 9, 2007 |
About: How scientists discovered groundbreaking medical treatments when they were looking for something else

Pros: Interesting, bibliography included

Cons: Some stories are more interesting than others

Grade: B ( )
  charlierb3 | Jul 12, 2007 |
Mostrando 5 de 5
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Happy Accidents is a fascinating, entertaining, and highly accessible look at the surprising role serendipity has played in some of the most important medical discoveries in the twentieth century. What do penicillin, chemotherapy drugs, X-rays, Valium, the Pap smear, and Viagra have in common? They were each discovered accidentally, stumbled upon in the search for something else. In the 1990s, Pfizer had high hopes for a new drug that would boost blood flow to the heart. As they conducted trials on angina sufferers, researchers noted a startling effect: while the drug did not affect blood flow to the heart, it did affect blood flow elsewhere! Now over six million American men have taken Viagra in their lifetime. Winston Churchill once said, "Men occasionally stumble across the truth, but most of them pick themselves up and hurry off as if nothing has happened." Within the scientific community, a certain stigma is attached to chance discovery because it is wrongly seen as pure luck. Happy accidents certainly happen every day, but it takes intelligence, insight, and creativity to recognize a "Eureka, I found what I wasn't looking for!" moment and know what to do next. In discussing medical breakthroughs, Dr. Morton Meyers makes a cogent, highly engaging argument for a more creative, rather than purely linear, approach to science. And it may just save our lives!

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