This compilation provides an overview of major classical neurotransmitters and their role in epilepsy. Stressing modern concepts of neurotransmitter action on neuronal membranes, the book offers pertinent data on the scientific basis for certain clinical approaches to brain disease and discusses considerations involved in addressing complex clinical disorders such as epilepsy. Among the topics discussed are second messenger systems and epilepsy; mechanisms of antiepileptic drug action; membrane channels and actions of anticonvulsants; the glutamate system and the NMDA receptor; genetic control; norepinephrine; and acetylcholine, serotonin, and opiates. Intended to bridge the gap between clinicians and researchers, it offers a state-of-the-art review of current information regarding this disease.