Cassie Harper is a disillusioned high school senior who is daily losing ground in a battle against her own nihilistic inclinations. When a beautiful new girl from California comes to town and attempts to befriend a reluctant Cassie, the two unlikely companions find common ground in a shared sorrow. Cassie lives with her mother and grandmother in a dilapidated house in a nameless Kansas town, where she is haunted nightly by dreams of a father who died before she was born. Amy Cole has just moved from California, where she recently lost her mother and brother in a car accident. When Amy finally breaks down the walls of Cassie's self imposed solitude, the girls band together to avoid the common end of all high school students: inexorable assimilation into an increasingly empty and incomprehensible world. But as Amy and Cassie attempt to outrun fate, their pursuit will be cut short by an unexpected adversary, leading Cassie to devise a chilling and unimaginable revenge. Cassie Draws the Universe is a complex and tragic tale of friendship and betrayal, living and dying, human cruelty, and the terrible price of vengeance.