In January 2014, Elise Schiller's youngest child, thirty-three-year-old Giana Natali, died of a heroin overdose while a resident in a treatment program in Boulder County, Colorado. Even if Your Heart Would Listen is about Giana's life, which was full of accomplishments, and her mental illness, addiction, and death. Using excerpts from the journals, planners, and letters Giana left behind, as well as evidence from her medical records, Schiller dissects her daughter's treatment for opioid use disorder (OUD) at the five residential and several outpatient programs in eastern Pennsylvania where she tried to recover, taking a close look at the lack of continuity and solid medical foundations in the American substance-use treatment system even as she explores the deeply personal experience of her own loss. Poignant and timely, Even if Your Heart Would Listen is a meditation on a family's grief, an intimate portrayal of a mother-daughter bond that endures, and an examination of how our nation is failing in its struggle with the opioid epidemic.